2CLX: 4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects

PDB ID: 2CLXDownload
MMDB ID: 42581
PDB Deposition Date: 2006/5/2
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2CLX: monomeric; determined by author and by software (PQS)
Molecular Components in 2CLX
Label Count Molecule
Protein (1 molecule)
1
Cell Division Protein Kinase 2
(Gene symbol: CDK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303